Browse Prior Art Database

Plasmapheresis System

IP.com Disclosure Number: IPCOM000081606D
Original Publication Date: 1974-Jul-01
Included in the Prior Art Database: 2005-Feb-28
Document File: 2 page(s) / 88K

Publishing Venue

IBM

Related People

Jones, AL: AUTHOR [+2]

Abstract

This system is designed to greatly simplify the procedure of plasmapheresis and to shorten the time required for the medical personnel as well as the donor. The basic attribute is in making the withdrawal of whole blood and reinfusion of packed red blood cells continuous. While this is happening, the plasma is being collected in special compartments in a container inside a spinning centrifuge bowl.

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Plasmapheresis System

This system is designed to greatly simplify the procedure of plasmapheresis and to shorten the time required for the medical personnel as well as the donor. The basic attribute is in making the withdrawal of whole blood and reinfusion of packed red blood cells continuous. While this is happening, the plasma is being collected in special compartments in a container inside a spinning centrifuge bowl.

A simplified schematic of the system is shown in Fig. 1. Blood is drawn from an arm vein of the donor, mixed with anticoagulant, and pumped by the whole blood pump P1 into the rotating centrifuge 3, of the type disclosed in U. S. Patent 3,737,096. The centrifuge bowl contains a disposable plastic bag 5 with a configuration as shown in Fig. 2.

The whole blood is delivered to the circumference as shown. As it flows around the circumference, it separates into packed red cells and plasma. At a point diametrically opposite to where the whole blood was delivered, the packed red cells are removed via the RBC pump P2. By controlling the relative flow rates of the whole blood and RBC pumps, plasma can be made to accumulate in the bag 5. The only place it can accumulate is in the two pouches marked "PLASMA COLLECT VOLUME".

Meanwhile, the packed red cells are being returned to the donor via pump P2. When two units (about 500 ml) of plasma have been collected, the whole blood pump P1 is stopped and the RBC pump P2 continued until plasma begins to be drawn int...