Browse Prior Art Database

Continuous Flow Dialyzer

IP.com Disclosure Number: IPCOM000083687D
Original Publication Date: 1975-Jul-01
Included in the Prior Art Database: 2005-Mar-01
Document File: 2 page(s) / 43K

Publishing Venue

IBM

Related People

Kellogg, RM: AUTHOR [+2]

Abstract

This dialyzer consists of a plasma pump 1, a dialyzate pump 3, a dialysis cell 5 and the related necessary controls.

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Continuous Flow Dialyzer

This dialyzer consists of a plasma pump 1, a dialyzate pump 3, a dialysis cell 5 and the related necessary controls.

The plasma pump 1 draws the plasma sample from a test tube through small plastic tubing, pumps it through one side of the dialysis cell and out into another test tube.

The dialyzate pump 3 draws the dialyzate from a suitable container and pumps it through the other side of the dialysis cell, in a direction opposite to the plasma flow.

The dialysis cell 5 is constructed of two plates 7 and 9 with a cavity, 0.003'' deep, etched in one side of each to act as a flow channel. The plates are assembled with the etched surfaces toward center, but separated by a cellophane membrane 11. The two channel sides are connected to the pumps by drilled holes and stainless steel tubing, suitable for the plastic tubing to be slipped onto.

The dialysis cell etched area has very small lands on centers of twice the dimension of the lands. The lands act as supports for the membrane 11 and also cause an even distribution of the flowing plasma. The alignment of the lands of one plate to the lands of the other plate, is controlled by a symmetrical land pattern and critically located orientation pins 13 and 15.

The unique purpose of this unit is to give a continuous flow dialysis of a low- volume sample. This is accomplished in the cell which has low volume but a large surface area.

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