Sample Preparation Method for MALDI Analysis
Original Publication Date: 2001-Mar-20
Included in the Prior Art Database: 2005-Jun-09
National Institute of Standards and Technology
Polyethylene and other polyolefins have not been amenable to MALDI or other soft ionization methods of characterization due to the ineffectiveness of conventional methods of cationization. The lack of polar groups, unsaturation, and aromaticity excludes cationization methods that are used for other common polymers. A new process has been invented in which an organic cation is covalently bonded to the polymer to produce the necessary ionization for successful MALDI. A strong MALDI signal results from polymers that give no response by other methods. This represents a major improvement in Polyolefin analysis and quality control. Other polymers such as styrenics can be analyzed by this method also.