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Polyetheretherketone (PEEK) Microtiter Plates for High Throughput Screening and Combinatorial Chemistry

IP.com Disclosure Number: IPCOM000126944D
Publication Date: 2005-Aug-15
Document File: 1 page(s) / 26K

Publishing Venue

The IP.com Prior Art Database

Abstract

The use of Polyetheretherketone (PEEK) as a material for making microtiter plates for high throughput screening (HTS) and combinatorial chemistry (CC) is disclosed. Also included is glass fiber filled PEEK (or PEEK containing) materials as microtiter plates. Microtiter plates such as current designs with various well volumes and shapes and number of wells (96, 384, 1536) can be made by processing techniques known in the art. Filters made from PEEK and other materials can also be incorporated into the plates for parallel filtration.

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Polyetheretherketone (PEEK) Microtiter Plates for High Throughput Screening and Combinatorial Chemistry

The use of Polyetheretherketone (PEEK) as a material for making microtiter plates for high throughput screening (HTS) and combinatorial chemistry (CC) is disclosed. Also included is glass fiber filled PEEK (or PEEK containing) materials as microtiter plates. Microtiter plates such as current designs with various well volumes and shapes and number of wells (96, 384, 1536) can be made by processing techniques known in the art.  Filters made from PEEK and other materials can also be incorporated into the plates for parallel filtration.

This polymer is widely regarded as the highest performance thermoplastic material currently available.  The high temperature performance and chemical resistance properties of PEEK are exceptionally good compared with other materials (including Teflon). This is very important since materials with a wide temperature range and resistance to a large number of chemicals are needed for high throughput screening and combinatorial chemistry in general.

Most of the microtiter plates that are currently available are made from polystyrene that has a temperature limit of about 90˚C and cannot be used with many of the common chemicals for HTS and CC such as organic solvents.

Some companies also offer polypropylene microtiter plates with a temperature limit of about 35˚C and more chemical resistance although warping and other undesirable effects are seen...