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Personal Care compositions comprising UV filters in combination with Keratin Binding Polypeptides

IP.com Disclosure Number: IPCOM000132571D
Publication Date: 2005-Dec-22

Publishing Venue

The IP.com Prior Art Database

Abstract

The invention describes the use of at least one UV-A and/or UV-B filter in combination with a Keratin Binding Polypeptide with binding affinity for human hair, skin or nail in Personal Care applications. The UV-A and/or UV-B filter may be covalently bound to the Keratin Binding Polypeptide. In all these Personal Care compositions the UV filters may be directly coupled to the Keratin Binding Polypeptide or they may be coupled by a spacer separating the Keratin Binding Polypeptide from the UV-A and/or UV-B filter. The UV-A and/or UV-B filters may be combined in such a concentration range that they boost the SPF (sun protection factor) in the Personal Care application. It is preferred that the combination of said UV-A and/or UV-B filters which could be attached to the Keratin Binding Polypeptide leads to a synergistic effect with regard to SPF.

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The invention describes the use of at least one UV-A and/or UV-B filter in combination with a keratin binding polypeptide (KBD) with binding affinity for human hair, skin or nail in Personal Care applications. The UV-A and/or UV-B filter may be covalently bound to the keratin binding polypeptide. In another embodiment the keratin binding polypeptide contains a spacer separating the keratin binding polypeptide from the UV-A and/or UV-B filter.

The UV-A and or UV-B filters could be combined in Personal Care applications in such a way that they act synergistically an offer a higher SPF (sun protection factor) than the sum of the single SPF's. It is preferred that the UV-A and/or UV-B filters act synergistically and boost the SPF of the Personal Care applications.

In further embodiments, compositions of the present invention comprise any organic UV-A and UV-B filter, for example but not limited:

Nr. Compound CAS-Nr.

(=Acid)

1 4-Aminobenzoicacid 150-13-0

2 3-(4'-Trimethylammonium)-benzylidenbornan-2-on- methylsulfat

3 3,3,5-Trimethyl-cyclohexyl-salicylat

(Homosalatum)

4 2-Hydroxy-4-methoxy-benzophenon

(Oxybenzonum)

5 2-Phenylbenzimidazol-5-sulfonicacid and their Calcium-,

Sodium- and. Triethanolaminosalts

6 3,3'-(1,4-Phenylendimethin)-bis(7,7-dimethyl-

2-oxobicyclo[2.2.1]heptan-1-methansolfonicacid) and salts thereof

4065-45-6

13 3-(4'-Sulfobenzyliden)-bornan-2-on and salts thereof 58030-58-6

14 3-Benzylidenbornan-2-on 16087-24-8

15 1-(4'-Isopropylphenyl)-3-phenylpropan-1,3-dion 63260-25-9

16 4-Isopropylbenzylsalicylat 94134-93-7

17 3-Imidazol-4-yl-acrylicacid und ihr Ethylester 104-98-3

18 2-Cyano-3,3-diphenylacrylicacidethylester 5232-99-5

19 2-Cyano-3,3-diphenylacrylicacid-2'-ethylhexylester 6197-30-4

52793-97-2

118-56-9

131-57-7

27503-81-7

90457-82-2

7 4-Bis(polyethoxy)amino-benzoesäurepolyethoxy-ethylester 113010-52-9

8 4-Dimethylamino-benzoicacid-2-ethylhexylester 21245-02-3

9 Salicylicacid-2-ethylhexylester 118-60-5

10 4-Methoxy-cinnamicacid-2-isoamylester 71617-10-2

11 4-Methoxy- cinnamicacid -2-ethylhexylester 5466-77-3

12 2-Hydroxy-4-methoxy-benzophenon-5-sulfonicacid-

(Sulisobenzonum) and the sodiumsalt

1

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20 Menthyl-o-aminobenzoat oder:

5-Methyl-2-(1-methylethyl)-2-aminobenzoat

21 Glyceryl p-aminobenzoat oder:

4-Aminobenzoicacid-1-glyceryl-ester

1641-17-4

24 Triethanolamin Salicylat 2174-16-5

25 Dimethoxyphenylglyoxalsäure oder:

3,4-dimethoxy-phenyl-glyoxal-saures Natrium

30 2,2'-(1,4-Phenylen)-bis-1H-benzimidazol-4,6- disulfonicacid, Sodiumsalt

31 2,4-bis-[4-(2-Ethylhexyloxy)-2-hydroxy]phenyl-

6-(4-methoxyphenyl)-(1,3,5)-triazin

3121-60-6

36 Benzoicacid, 2-[4-(diethylamino)-2-hydroxybenzoyl]-, hexylester 302776-68-7

37 2-(2H-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3- tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]phenol

134-09-8

136-44-7

22 2,2'-Dihydroxy-4-methoxybenzophenon (Dioxybenzone) 131-53-3

23 2-Hydroxy-4-methoxy-4-methylbenzophenon

(Mexenon)

4732-70-1

26 3-(4'Sulfobenzyliden)-bornan-2...