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Aspergillus niger fermentations

IP.com Disclosure Number: IPCOM000174101D
Publication Date: 2008-Aug-26
Document File: 1 page(s) / 24K

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We have developed a new control strategy for Aspergillus

niger

fermentations based on polyol/glycerol measurements.

The proposed strategy has led to yield improvements in A.

niger

amylase fermentations.

The new control strategy provides a method for increasing yield and productivity of protein expression in A.

niger

fermentations by inducing late stage hyphae fragmentation and viscosity reduction via carbon starvation and subsequent carbon dosing strategy.