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Drug Coated Balloons: A method to make a balloon with precise pockets

IP.com Disclosure Number: IPCOM000182444D
Publication Date: 2009-Apr-30
Document File: 1 page(s) / 20K

Publishing Venue

The IP.com Prior Art Database

Abstract

This idea is a method to create a balloon catheter with similar sized micro pockets or dimples that can be used for drug delivery. The amount of drug release is controlled by the specific volume of the pocket size and the internal pressure of the balloon.

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Drug Coated Balloons: A method to make a balloon with precise pockets

This idea is a method to create a balloon catheter with similar sized micro pockets or dimples that can be used for drug delivery.  The amount of drug release is controlled by the specific volume of the pocket size and the internal pressure of the balloon.

The idea is to cover the internal wall of the balloon mold with similar sized particles or spheres. During the balloon molding process, the balloon material will flow over these spheres and are incorporated within the wall structure. Then these spheres are removed from the balloon wall leaving pockets incorporated into the catheter structure. Drug particles are filled into these pockets or are incorporating in the mold which can be directly loaded into the pockets during formation.

The balloon molds are coating with spheres using a layer-by-layer process. The spheres could be made from several materials including polystyrene, polystyrene magnetite mixture, magnetic particles, water soluble salts, water soluble organics like sugar or polymers there of. Using a layer-by-layer process to coat the internal balloon mold produces a well distributed single layer of spheres. When the balloon is deflated after the molding step, the spheres remain with the balloon wall with minimal force.

Drug particles are deposited by several well know methods including sparse spraying these onto the balloon surface, dip c...