Browse Prior Art Database

Integration of functional Ultrasound Imaging into Cathlab diagnostics

IP.com Disclosure Number: IPCOM000184870D
Original Publication Date: 2009-Jul-23
Included in the Prior Art Database: 2009-Jul-23
Document File: 3 page(s) / 33K

Publishing Venue

Siemens

Related People

Juergen Carstens: CONTACT

Abstract

stenosis, restenosis, thrombosis or aneurismal enlargement of coronary arteries. In general interventional procedures provide information on lesion size and luminal narrowing due to the direct access via the arterial system. However, coronary angiography provides none or only very limited information about atherosclerotic plaque composition or the functional impact of stenosis/occlusions on the myocardium. Furthermore, the intervention is carried out in the catheterization laboratory. During the intervention closed arteries due to stenosis are reopened by well known angioplasty or stenting procedures. One major problem after the procedure is the so-called “no reflow” phenomena.

This text was extracted from a PDF file.
At least one non-text object (such as an image or picture) has been suppressed.
This is the abbreviated version, containing approximately 24% of the total text.

Page 1 of 3

Integration of functional Ultrasound Imaging into Cathlab diagnostics

Idee: Dr. Thomas Redel, DE-Forchheim; Dr. Estelle Camus, US-Mountain View; Dr. Chi-Yin Lee,
US-Issaquah

Coronary artery disease is still the main cause of death and disabilities in industrialized countries. Coronary catheterization is a minimal invasive imaging method for interventional therapy of occlusion, stenosis, restenosis, thrombosis or aneurismal enlargement of coronary arteries. In general interventional procedures provide information on lesion size and luminal narrowing due to the direct access via the arterial system. However, coronary angiography provides none or only very limited information about atherosclerotic plaque composition or the functional impact of stenosis/occlusions on the myocardium. Furthermore, the intervention is carried out in the catheterization laboratory. During the intervention closed arteries due to stenosis are reopened by well known angioplasty or stenting procedures. One major problem after the procedure is the so-called "no reflow" phenomena. Although the coronary is open, there is no or only a limited flow into the distal part of the coronary as well as the perfusion of the myocardium is reduced. Therefore, it is advantageous to obtain immediately information about the perfusion status of the myocardium in relation to the blood flow in the coronaries. Furthermore, it is advantageous to display the information in the catheterization laboratory, i.e. before the end of the interventional procedure. In addition, further information on the functional status would be beneficial for a better prognosis of the health status of the patient. In general the described problem emerges also with other organs and their supplying or drainage vessels. Up to now, there are different options for the functional assessment of the myocardium. Multi- slice scanners and cardiac CT are used as a non-invasive method for imaging coronary arteries (CT: computed Tomography). CT imaging with or without intravenous iodine-based contrast can visualize reliably the cardiac anatomy and offers the possibility for 3D reconstruction. The method can be used in different phases of the heart cycle so that the movement of the heart muscle can be analyzed. However, CT imaging method can not be used during interventional procedures, because it is not practicable to carry the patient to the CT scanner during an interventional procedure. The Cardiac MRI method is particularly useful for evaluating the cardiovascular system (MRI: Magnetic Resonance Imaging). In addition to being non-invasive and risk-free, MRI acquires information about the heart as well as its beating. Therefore, moving images of the heart can be generated throughout the pumping cycle. Then Abnormalities in the cardiac chamber contraction can be displayed and abnormal patterns of b...