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Bimetallic Self-Expanding Coil for Cryothermal Renal Nerve Ablation

IP.com Disclosure Number: IPCOM000201502D
Publication Date: 2010-Nov-12
Document File: 1 page(s) / 29K

Publishing Venue

The IP.com Prior Art Database

Abstract

The invention is apparatus and methods for improved contact and control in cryothermal ablation of perivascular renal nerves for control of hypertension. Prior approaches often have problems in obtaining good contact between an intravascular ablation device and the vessel wall, resulting in ineffective ablation of target nerves, or resulting in unwanted injury to arterial wall tissue. The invention utilizes the bending of bimetallic strips, in which metals of differing thermal expansion coefficients are bonded or clad together. As the temperature is raised or lowered from a neutral temperature, the strip bends one way or the other from a neutral orientation. A coil or other structure incorporating bimetallic components will expand outward toward the artery wall, or inward away from the artery wall, depending on the temperature of those components. When using an ablation device that uses lowered temperature (cryoablation) or raised temperature (electrical or RF heating, for example) the bimetallic components will deform to cause expansion and improved vessel wall contact when the ablation device is activated. When the ablation device is deactivated, the bimetallic components will deform to move elements of the ablation device away from the vessel wall, such as form lower profile introduction or removal of the device. An ablation device incorporating the bimetallic structures will then automatically self-deploy to achieve good vessel wall contact when the device is activated, and return to a low profile configuration when the device is deactivated.

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The invention is apparatus and methods for improved contact and control in cryothermal ablation of perivascular renal nerves for control of hypertension. Prior approaches often have problems in obtaining good contact between an intravascular ablation device and the vessel wall, resulting in ineffective ablation of target nerves, or resulting in unwanted injury to arterial wall tissue. The invention utilizes the bending of bimetallic strips, in which metals of differing thermal expansion coefficients are bonded or clad together. As the temperature is raised or lowered from a neutral temperature, the strip bends one way or the other from a neutral orientation. A coil or other structure incorporating bimetallic components will expand outward toward the artery wall, or inward away from the artery wall, depending on the temperature of those components.

When using an ablation device that uses lowered temperature (cryoablation) or raised temperature (electrical or RF heating, for example) the bimetallic components will deform to cause expansion and improved vessel wall contact when the ablation device is activated. When the ablation device is deactivated, the bimetallic components will deform to move elements of the ablation device away from the vessel wall, such as form lower profile introduction or removal of the device. An ablation device incorporating the bimetallic structures will then automatically self-deploy to achieve good vessel wall contact when the device is activated,...