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DEVICES, SYSTEMS, AND METHODS REALTED TO PELVIC HEALTH AND DISORDERS THEREOF

IP.com Disclosure Number: IPCOM000240248D
Publication Date: 2015-Jan-15
Document File: 3 page(s) / 60K

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The IP.com Prior Art Database

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DEVICES, SYSTEMS, AND METHODS REALTED TO PELVIC HEALTH AND DISORDERS THEREOF   

PERIODIC SACRAL NERVE STIMULATION THERAPY DELIVERED AS A WEEKLY OR SIMILARLY EXTENDED  DUTY CYCLE OF STIMULATION TO PRODUCE A LONG LASTING EFFECT AS A TREATMENT FOR 

OVERACTIVE BLADDER OR SIMILAR DISORDERS 

Currently sacral nerve stimulation therapy is delivered as a continuous therapy or with a duty cycle of several seconds or minutes with stimulation "on" coupled with seconds or minutes (to hours) of stimulation "off". This invention describes an extended duty cycle therapy e.g. 30-60 min stimulation-on with a week or more weeks off duration. In our testing of the therapy in sheep, we observed that therapeutic action likely has a long lasting effect (persisting up to a week or more) following a period of stimulation (approximately 30-60 minutes). The time course response to sacral nerve neuromodulation should be same in humans. The extended duty cycle therapy delivery schedule allows a stimulation to be focused onto one time and the therapy (relief from symptoms) it provides can at a different time of the day or week. Therapy, for example, can be delivered intermittently or delivered using a weekly or similar periodic schedule of stimulation session or period followed by extended periods of no stimulation or alternative stimulation periods with the knowledge that the therapy will be effective at a different time or series of times. Periodic sacral nerve stimulation may allow longer lasting battery systems or the use of devices that do not have battery or are powered externally using RF or similar systems requiring external fields or stimulation equipment. For example a system could be implanted to allow pass through of stimulation over a short period of time, time of day or time of week or month… with therapy that is longer lasting. The external equipment needed for delivery of therapy may not be conducive to constant or more frequent use but may be conducive to less frequent use as described here. Extended periods of stimulation may allow use of smaller stimulation devices or even unpowered therapy devices (RF or similar) for use in patients with less severe disorders or for patients earlier in the care continuum. Periodic sacral nerve stimulation may allow longer persistence for a potential therapy (if therapy itself is considered to be causing decrease of therapeutic effect). For example stimulation delivery may have some negative side effects (e.g. motor responses or sensory responses or similar neural responses). Less frequent or shorter duration delivery of the therapy may allow these effects to be avoided or focused onto specific times that a patient or system can endure. Periodic sacral nerve stimulation may also allow a patient to better receive stimulation if side effects of the therapy are undesirable or unwanted and limiting therapy delivered. Periodic sacral nerve stimulation may allow therap...