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FUSION OF CARDIAC FUNCTIONAL PARAMETERS WITH X-RAY FLOUROSCOPY

IP.com Disclosure Number: IPCOM000240786D
Publication Date: 2015-Mar-02
Document File: 3 page(s) / 57K

Publishing Venue

The IP.com Prior Art Database

Abstract

The invention proposes a technique to create a fused display of functional parameters, such as peak-strain and time-to-peak strain with x-ray flouroscopy. The functional parameters are acquired from cardiac ultrasound, cardiac magnetic resonance imaging (MRI) or computer tomography (CT). The proposed technique allows for spatially alignment of the 3D generic heart model with 2D X-ray fluoroscopy. The spatially distributed cardiac parameters are based on measurement from a specific patient. The parameters are mapped to a generic 3D anatomic heart model. The generic heart model is registered with 2D X-ray images of the patient. The overlayed cardiac parameters are visualized and spatially aligned with the 2D X-ray images of the patient.

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FUSION OF CARDIAC FUNCTIONAL PARAMETERS WITH X-RAY FLOUROSCOPY

BACKGROUND

The present invention relates generally to cardiac functional parameters and more particularly to fusion of cardiac functional parameters with X-ray fluoroscopy.

Generally, cardiac resynchronization therapy (CRT) is effective in treating patients with cardiac arrhythmias. However, only 70% of patients who receives a CRT device respond favorably to the treatment. This is partly due to suboptimal criterion for selecting patients for CRT and partly due to sub-optimal placement of CRT leads. The best position for placement of left ventricular (LV) lead in CRT is at a site of latest mechanical activation. However, it is required to avoid ischemic tissue areas.

In a conventional technique, ultrasound strain imaging is used to identify the best position for the LV lead. The information about the best position of LV lead is required to be superimposed on X-ray fluoroscopy. In order to provide such a fused display, a registration between ultrasound or magnetic resonance imaging (MRI) image space and X-ray image space is required to be computed. However, it is not easy to find corresponding structures in ultrasound and X-ray that is desired to be aligned to produce the registration.

Another conventional technique determines placement positions of the lead within the left ventricle (LV) prior to CRT implantation procedure. However, the technique uses a patient-specific model of the left ventricle and the method of registration varies from manual method to automatic method.

One other conventional technique integrates multiple data sources with X-ray images generated by X-ray imaging systems. The technique also collects information from sensors of a catheter disposed within a subject. However, the above technique uses functional data from ultrasound and not from sensors of the catheter disposed within a tissue.

It would be desirable to have an efficient technique to acquire fused display of functional parameters acquired from cardiac ultrasound or cardiac magnetic resonance imaging (MRI), and X-ray fluoroscopy.

DETAILED DESCRIPTION

The present invention proposes a technique to create a fused display of functional parameters (e.g.  peak-strain or time-to-peak strain) and X-ray flouroscopy. The functional parameters are acquired from cardiac ultrasound, cardiac magnetic resonance imaging (MRI) or computer tomography (CT) and fused with X-ray fluoroscopy using a simple registration procedure.

A segmental model of left ventricle is defined conventionally. The model provides anatomical labels to each of the segments. The anatomical labels are directly related to views in ultrasound and MRI. The technique maps segments...