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INJECTABLE POLYMER AND DELIVERY SYSTEM FOR OCCLUSION OF INTRAHEPATIC DUCTS AND VESSELS

IP.com Disclosure Number: IPCOM000246870D
Publication Date: 2016-Jul-08
Document File: 2 page(s) / 160K

Publishing Venue

The IP.com Prior Art Database

Abstract

In a surgical resection of a liver there are several aspects that can affect blood loss. This blood loss prevents several challenges for the surgical procedure. First and of foremost intraoperative concern is that blood obscures the field of view of the surgeon. Challenges in a liver resection include cutting through the parenchyma, or body, of the liver in a manner that allows for sealing of bile ducts, and large and small vessels. Numerous technologies and approaches are used for transection through parenchyma; they range from simple to complex. Simple methods include crushing with basic clamps or jawed instruments. More technologically complex methods include ultrasonic fracturing and evacuation. In each of these approaches there is concern that bile ducts or blood vessels that reside within the parenchyma can be fractured resulting in bile or blood loss. A significant concern for blood loss is for obvious patient reasons, with greater than a critical amount of blood loss; blood transfusions with the related complication risks are needed. An additional concern for bile duct fracture is the resultant risk for intraoperative or postoperative bile leak. Intraoperative bile leak can lead to prolonged procedure time. Post‐operative bile leak can lead to infection, other complications and an increase risk of liver failure.

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INJECTABLE POLYMER AND DELIVERY SYSTEM FOR OCCLUSION OF INTRAHEPATIC DUCTS AND VESSELS 

 

SUMMARY 

In a surgical resection of a liver there are several aspects that can affect blood loss.  This blood loss  prevents several challenges for the surgical procedure.  First and of foremost intraoperative concern is  that blood obscures the field of view of the surgeon.  Challenges in a liver resection include cutting  through the parenchyma, or body, of the liver in a manner that allows for sealing of bile ducts, and large  and small vessels.  Numerous technologies and approaches are used for transection through  parenchyma; they range from simple to complex. Simple methods include crushing with basic clamps or  jawed instruments.  More technologically complex methods include ultrasonic fracturing and  evacuation.  In each of these approaches there is concern that bile ducts or blood vessels that reside  within the parenchyma can be fractured resulting in bile or blood loss. 

A significant concern for blood loss is for obvious patient reasons, with greater than a critical amount of  blood loss; blood transfusions with the related complication risks are needed. 

An additional concern for bile duct fracture is the resultant risk for intraoperative or postoperative bile  leak.  Intraoperative bile leak can lead to prolonged procedure time.  Post‐operative bile leak can lead to  infection, other complications and an increase risk of liver failure. 

 

DESCRIPTION 

In the re...