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Protection against near infrared radiation (IR-A), visible (VIS) and high energy light (HEV) with inorganic UV filters Michael Termer*, Jutta zur Lage*, Anett Moschner*, Frank Pflücker* *Merck, Pigments & Functional Materials, Darmstadt, Germany

IP.com Disclosure Number: IPCOM000249708D
Publication Date: 2017-Mar-23

Publishing Venue

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Abstract

Summary The present publication relates to cosmetic oil-in-water (O/W), water-in-oil (W/O), water-in-silicones (W/Si), water-in-oil-in-water (W/O/W), oil-in-water-in-oil (O/W/O) or gels comprising coated Titanium dioxides (NANO) in order to provide protection against near infrared radiation (IR-A: 800 – 1450 nm), visible (VIS: 400 – 800 nm) and high energy light (HEV: 400 – 500 nm).

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Protection against near infrared radiation (IR-A), visible (VIS) and high

energy light (HEV) with inorganic UV filters

Michael Termer*, Jutta zur Lage*, Anett Moschner*, Frank Pflücker* *Merck, Pigments & Functional Materials, Darmstadt, Germany

Summary

The present publication relates to cosmetic oil-in-water (O/W), water-in-oil (W/O), water-in-

silicones (W/Si), water-in-oil-in-water (W/O/W), oil-in-water-in-oil (O/W/O) or gels

comprising coated Titanium dioxides (NANO) in order to provide protection against near

infrared radiation (IR-A: 800 – 1450 nm), visible (VIS: 400 – 800 nm) and high energy light

(HEV: 400 – 500 nm).

1. Introduction

The solar spectrum is composed of various wavelength radiations having specific as well as

overlapping and synergistic effects on skin as shown in figure 1.

Figure 1: Composition of sunlight and its effects. UV = ultraviolet radiation; ROS = reactive oxygen species; RNS =

reactive nitrogen species.

UVB is responsible for most sunburn, although short wavelength UVA may also trigger

erythema to a lesser extent. Both UVB and UVA alter the immune response either alone or

together, but given that UVA is 20 times more abundant in sunlight, the latter is generally

considered the main culprit in solar-induced immunosuppression.

Visible light mainly affects skin through the generation of oxidative damage, whereas IR

induces additionally heat damage and alters mitochondrial integrity in skin cells, resulting also

in ROS generation.

Nearly 50 % of free radicals formed by solar radiation are deriving from visible and IR light.

IR-A (800 to 1450 nm) and high energy visible light (400 – 500 nm) also called “blue light”

leads to a significant degradation of cutaneous carotenoid antioxidants.

All solar wavelengths contribute altogether to photoaging of the skin due to ROS/RNS

generation. It is therefore necessary to develop skin care or sun care products not only with

an UVB/UVA protection but also in addition with HEV and IR-A protection for maintenance of

skin health.

It has been found that cosmetic formulations such as O/W, W/O, W/O/W, O/W/O, W/Si or gels

containing coated nano titanium dioxide can provide a high level of protection against IR-A,

VIS and HEV light.

2. Material, Methods & Results

2.1 Used Titanium Dioxide

Table 1: Overview of used Nano TiO2

Name INCI Article

number

Supplier

Eusolex® T-PRO Titanium Dioxide, Alumina, Manganese Dioxide

105337 Merck KGaA

UV-TITAN™ M 765 Titanium Dioxide, Alumina, Triethoxy caprylylsilane

SACL765 Merck KGaA

Eusolex® T-AVO Titanium dioxide, Silica 105335 Merck KGaA

Eusolex® T-S Titanium Dioxide (nano), Alumina, Stearic Acid

105334 Merck KGaA

UV-TITAN™ M 212 Titanium Dioxide (nano), Alumina, Glycerine

SACL212 Merck KGaA

UV-TITAN™ M 262 Titanium Dioxide, Alumina, Dimethicone

SACL262 Merck KGaA

Eusolex® T-EASY Titanium Dioxide, Silica, Cetyl Phosphate

105338 Merck KGaA

UV-TITAN™ M 170 Titanium Dioxide, Alumina, Hydrogen Dimethicone

SACL170 Merck KGaA

UV-TITAN™ M 160 Titanium Dio...