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Characterization of Sorbic Acid and Its Oxidation Degradants Using HPLC-ESI-MS, and HPLC-MALDI-TOF MS

IP.com Disclosure Number: IPCOM000005572D
Publication Date: 2001-Oct-16

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In this study the combination of GPC and HPLC with ESI and MALDI time of flight (TOF) MS are used to elucidate oxidative products and polymeric materials formed from degradation of sorbic acid. Degradation products from aqueous model systems and pharmaceutical products are compared. To date we have verified the degradation products of sorbic acid to have a copolymer composition of acrolein and -carboxy acrolein monomers.