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THE INFLUENCE OF SUSTAINED RELEASE COATING PLASTICIZER ON THE RELEASE PROFILE OF A SOLUBLE DRUG FROM PELLETS

IP.com Disclosure Number: IPCOM000006964D
Publication Date: 2002-Feb-12

Publishing Venue

The IP.com Prior Art Database

Abstract

The effect of plasticizers in insoluble sustained release film coating on the in vitro dissolution release of 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl] cyclohexanol hydrochloride from multiparticulate delivery systems (e.g. in tablets, capsules etc.) was studied. The findings are equally applicable to coatings on monolithic tablets.