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Lansoprazole Intermediate - TFPB Crystal Forms

IP.com Disclosure Number: IPCOM000016611D
Publication Date: 2003-Jul-03

Publishing Venue

The IP.com Prior Art Database

Abstract

2-[((3-Methyl-4-(2,2,2-Trifluoroethoxy)-2-Pyridinyl)-Methyl)-Thio]-1H-Benzimidazole (TFPB) is used as intermediate in the preparation of Lansoprazole. Various samples of TFPB were analyzed by X-Ray Powder diffraction and found to contain different crystal forms (I, II, III, IV).