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Use of a Low Resolution Mass Spectrometer to Separately Determine Impurities Having the Same Nominal Mass Disclosure Number: IPCOM000019381D
Publication Date: 2003-Sep-12

Publishing Venue

The Prior Art Database


Quantitative determination of compounds with the same nominal masses has not been possible on a continuous real time basis using a low resolution mass selective detector, like a quadrupole. The classical example of this is nitrogen and carbon monoxide which both have a nominal mass of 28. Another example is carbon dioxide and nitrous oxide which have a nominal mass of 44. The response which is obtained at these masses is due to the presence of both compounds. In order to separate the response from both compounds a high resolution mass spectrometer needs to be used. However, this increases both the expense and the complexity of the analytical instrument. In many instances it is important to obtain the data on a continuous basis using a low resolution mass selective analyzer in order to fully characterize various processes. Another reason for using this type of detector is for the unique high sensitivity achievable with an instrument such as an Atmospheric Pressure Ionization Mass Spectrometer (APIMS).