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Synergistic Fungicidal Compositions of Heterocyclic Aromatic Amides and Triazoles Disclosure Number: IPCOM000029972D
Publication Date: 2004-Jul-20

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A composition useful for protecting a plant against attack by a phytopathogenic organism comprising a picolinamide and a triazole.

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A composition useful for protecting a plant against attack by a phytopathogenic organism and/or treatment of a plant infested by a phytopathogenic organism has been developed which comprises a first compound represented by one of formulas I to IV:

and a second compound which is a triazole fungicide.  The first compound of the synergistic composition is a fungicidal heterocyclic aromatic amide (picolinamide) which is a derivative of the natural fungicide UK-2A (Ueki et al., Journal of Antibiotics, 1996, 49(7), 639).

Structure of UK-2A

Reference to the formulas I-IV includes hydrates, salts and complexes thereof. 

The triazoles useful in the synergistic composition of the present invention include any triazole which will provide synergistic fungicidal effect in combination with the heterocyclic aromatic amide of formula I-IV.  Such triazoles include, but are not limited to, epoxiconazole, propiconazole, cyproconazole, tebuconazole, fenbuconazole and the like.

Typically, the ratio of the heterocyclic aromatic amide to the triazole will be a ratio which exhibits synergistic effect in the prevention and/or curing of disease caused by fungi.  In general, synergy is exhibited when the combination of the two compounds demonstrates better disease control than what is expected when the two independent fungicides are applied alone.  Generally, the ratio will be from 0.1 to 10 and preferably from 0.2 to 5 by weight.

A fungicidally effective amount of the synergistic composition of a heterocyclic aromatic amide and a triazole is applied to soil, any part of a plant, foliage, and/or seeds.  The synergistic composition is applied by any technique, including as the synergistic composition, as a formulation, as the individual compounds in succession, as individual formulations containing each component in succession or as separate formulations applied simultaneously. 

The synergistic composition can be applied as any formulation type, e.g. solutions, dusts, wettable powders, flowable concentrates, or emulsifiable concentrates and the like.

Concentrated formulations can be dispersed in water, or other liquid, for application, or formulations can be dust-like or granular, which are applied without further treatment. 

The formulations that are applied most often are aqueous suspensions or emulsions.  Either such water-soluble, water suspendable, or emulsifiable formulations are solids; usually known as wettable powders, or liquids; usually known as emulsifiable concentrates, aqueous suspensions, or suspension concentrates. 

Wettable powders, comprise a mixture of the synergistic composition, a carrier and agriculturally acceptable surfactants.  The concentration of the synergistic composition in the wettable powder is usually from 10% to 90% by weight based on the total weight of the powder, more preferably 25% to 75% .   In the preparation of wettable powder formulati...