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Diagnostic Screening of Biological Specimens for Microscopy Disclosure Number: IPCOM000039815D
Original Publication Date: 1987-Aug-01
Included in the Prior Art Database: 2005-Feb-01

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Brady, MJ Feder, R Shaw, JM [+details]


X-ray microscopy of biological objects requires extensive processing in order to obtain a relief structure in X-ray resists, such as PMMA. Once the relief structure is obtained, a Scanning Electron Microscope (SEM) produces a magnified picture of the resist relief image. The amount of time required in processing, from start to finish, is often wasted due to the inability of the specimen to selectively absorb the X-rays, or due to incorrect exposure times, and at no point in the process is the probability of success indicated. A way is described for implementing a diagnostic or screening technique that reduces or eliminates the processing time required on specimens that will not deliver the required structure.