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DEVICE FOR MONITORING pH Disclosure Number: IPCOM000043115D
Original Publication Date: 1984-Jul-01
Included in the Prior Art Database: 2005-Feb-04

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Studebaker, JF [+details]


This article relates generally to devices for monitoring pH and more particularly to pH monitoring devices useful with columns for treating blood plasma. "Affinity Chromatography," a powerful method of purifying proteins and other molecules of biological origin, has been used for over twelve years in research laboratories and in some industrial processes [1]. It is now being applied to "on-line" extraction of pathological molecules from patients' blood plasma, which is first separated from the blood cells on a separator like the IBM 2997 (Fig. 1) [2,3]. The high cost of the column-packing materials makes it attractive to use two or more columns, which are used one-by-one until saturated, regenerated with appropriate solutions, and used again (Fig. 2).