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Nerve Regenerator Disclosure Number: IPCOM000064276D
Original Publication Date: 1985-Jun-01
Included in the Prior Art Database: 2005-Feb-18

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Chaudhari, P Costa, J Feder, R Sayre, D [+details]


A clamp-type device for assisting in the rejoining of a severed nerve is described. The clamp is fabricated from silicon, coated with silicon nitride and polymethylmethacrylate (PMMA) in the parallel channels formed by the clamp. The proximal end of a severed peripheral nerve will attempt to regenerate by sending out neurites. If the cut ends are physically opposed, some of these proximal neurites will enter the distal portion of the nerve, and have the capacity to continue their growth down axon sheats (tubes of supporting cells) which remain in this portion. For many reasons, including proliferation of the supporting cell-types in the proximal region of the injury, the growing neurites fail to make contact with an appropriate axon sheat in the distal stump.