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Publication Date: 2010-Feb-16
Document File: 5 page(s) / 55K

Publishing Venue

The Prior Art Database


Abstract: This disclosure pertains to the use of 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6 [(methylamino)¬carbonyl]¬phenyl]-1H-pyrazole-5-carboxamide as a fungicide, bactericide and viricide.

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This disclosure pertains to the use of 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6‑[(methylamino)­carbonyl]­phenyl]-1H-pyrazole-5-carboxamide (Compound 1) as a fungicide, bactericide and viricide.

The control of plant diseases caused by fungal, bacterial and viral plant pathogens is extremely important in achieving high crop efficiency.  Plant disease damage to ornamental, vegetable, field, cereal, and fruit crops can cause significant reduction in productivity and thereby result in increased costs to the consumer.  Many products are commercially available for these purposes, but the need continues for new compounds which are more effective, less costly, less toxic, environmentally safer or have different sites of action.

Compound 1 is known to be useful as an insecticide, and can be prepared as described in  U.S. Patent Nos. 6,747,047 and 7,247,647.

Compound 1 can generally be applied as a formulation or a composition with a carrier suitable for agronomic uses comprising at least one of a liquid diluent or a surfactant.  Suitable formulations are disclosed in U.S. Patent Nos. 6,747,047 and 7,247,647.

The formulations will typically contain effective amounts of active ingredient, diluent and surfactant within the following approximate ranges which add up to 100 percent by weight.  Said formulated composition can then be diluted with water to the desired application rates.  Examples of suitable compositions comprising Compound 1 as active ingredients include liquid compositions comprising water, organic solvent, or oil as a liquid diluent.

  Weight Percent

  Active Ingredient Diluent Surfactant

Water-Dispersible and Water-soluble Granules, Tablets and Powders.                    0.001–90   0–99.999              0–15

 Suspensions, Emulsions, Solutions (including Emulsifiable Concentrates)                            1–50        40–99              0–50

Dusts                            1–25        70–99              0–5

Granules and Pellets                    0.001–99        5–99.999              0–15

High Strength Compositions                          90–99           0–10              0–2

For further information regarding the art of formulation, see T. S. Woods, “The Formulator’s Toolbox – Product Forms for Modern Agriculture” in Pesticide Chemistry and Bioscience, The Food–Environment Challenge, T. Brooks and T. R. Roberts, Eds.,  Proceedings of the 9th International Congress on Pesticide Chemistry, The Royal Society of Chemistry, Cambridge, 1999, pp. 120–133.  See also U.S. 3,235,361, Col. 6, line 16 through Col. 7, line 19 and Examples 10–41; U.S. 3,309,192, Col. 5, line 43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138–14...