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Stability of KappaSelect Affinity Chromatography Media

IP.com Disclosure Number: IPCOM000216328D
Publication Date: 2012-Mar-30

Publishing Venue

The IP.com Prior Art Database

Abstract

KappaSelect, an affinity chromatography media with a protein ligand binding to Fab kappa or lambda light chain, was cleaned/sanitized with a sequence of 0.1 M citric acid, 10 mM NaOH and PAB (a pH 1.5 aqueous solution of phosphoric acid, acetic acid and benzyl alcohol). No loss in capacity could be observed after 25 cycles.