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ID: DIXON MR Elastography Disclosure Number: IPCOM000237137D
Publication Date: 2014-Jun-05
Document File: 1 page(s) / 24K

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ID: DIXON MR Elastography

Problem description

MRE sequences normally use Gradient Echo readouts (FFE) for phase-sensitive motion encoding, synchronized to an externally imposed, pseudo-continuous, shear wave in the human body.

The echo time of these sequences is normally long since the motion encoding gradients (MEG) have to encode the displacements related to the frequency of the external driver (typically 60 Hz). As a result, gradient echo sequences are reported to behave somewhat poorly at 3T, and have been replaced by spin echo EPI sequences. Allegedly, issues increase for fatty livers, and can be improved by subtle echo time modifications

Prior art:

FFE and SE-EPI with motion encoding gradients, triggered to the external wave imparting device, measured with in-phase echo time.

Proposed new method

Combine 2 or 3 point DIXON with the MRE motion encoding gradients in the FFE sequence.

Derive the water-only, fat-only and water&fat image. This makes the input date for the MRE processing less echo time dependent.

Evaluate the shear waves and stiffness based on the image with the best wave characteristics, probably the water&fat image.