PROCESS FOR THE PREPARATION OF ODANACATIB
Publication Date: 2016-Jun-27
The IP.com Prior Art Database
The present disclosure relates to a novel process for the preparation of odanacatib
Odanacatib (MK-0822) is a cathepsin K inhibitor being developed for the treatment of osteoporosis and bone metastasis.
Odanacatib is chemically named (2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino] pentanamide and is represented by the following chemical structure:
The present disclosure relates to a novel process for the preparation of odanacatib, which represents in following schemes.